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NCNPブレインバンク 研究業績 2013-2018(PDF)

NCNPブレインバンク 研究業績

《 2013 》
・Satoh J, Tabunoki H, Ishida T, Saito Y, Arima K. Accumulation of a repulsive axonal guidance molecule RGMa in amyloid plaques: a possible hallmark of regenerative failure in Alzheimer's disease brains. Neuropathol Appl Neurobiol. 39 (2): 109-20, 2013
・Yonekawa T, Komaki H, Saito Y, Takashima H, Sasaki M. Congenital hypomyelinating neuropathy attributable to a de novo p.Asp61Asn mutation of the myelin protein zero gene. Pediatr Neurol. 48 (1): 59-62, 2013
・Yonekawa T, Komaki H, Saito Y, Sugai K, Sasaki M. Peripheral nerve abnormalities in pediatric patients with spinal muscular atrophy. Brain Dev. 35 (2): 165-71, 2013
・Satoh J, Kawana N, Yamamoto Y, Ishida T, Saito Y, Arima K. A survey of TREM2 antibodies reveals neuronal but not microglial staining in formalin-fixed paraffin-embedded postmortem Alzheimer’s brain tissues. Alzheimers Res Ther. 5 (4): 30-2, 2013
・Nagai S, Saito Y, Endo Y, Saito T, Sugai K, Ishiyama A, Komaki H, Nakagawa E, Sasaki M, Ito K, Saito Y, Sukigara S, Ito M, Goto Y, Ito S, Matsuoka K. Hypoalbuminemia in early onset dentatorubral-pallidoluysian atrophy due to leakage of albumin in multiple organs. J Neurol. 260 (5): 1263-71, 2013
・Dan A, Takahashi M, Masuda-Suzukake M, Kametani F, Nonaka T, Kondo H, Akiyama H, Arai T, Mann MA David, Saito Y, Hatsuta H, Murayama S, Hasegawa M. Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer's disease brain. Acta Neuropathol Commun. 1: 54-63, 2013
・Tachibana N, Kinoshita M, Saito Y, Ikeda S. Identification of the N-Methyl-D- aspartate receptor (NMDAR)-related epitope, NR2B, in the normal human ovary: implication for the pathogenesis of anti-NMDAR encephalitis. Tohoku J Exp Med. 230 (1): 13-6, 2013
・Wen Y, Miyashita A, Kitamura N, Tsukie T, Saito Y, Hatsuta H, Murayama S, Kakita A, Takahashi H, Akatsu H, Yamamoto T, Kosaka K, Yamaguchi H, Akazawa K, Ihara Y, Kuwano R. SORL1 is genetically associated with neuropathologically characterized late-onset Alzheimer’s disease, J Alzheimers Dis. 35 (2): 387-94, 2013
・Sakurai Y, Ishii K, Sonoo M, Saito Y, Murayama S, Iwata A, Hamada K, Sugimoto I, Tsuji S, Mannen T. Progressive apraxic agraphia with micrographia presenting as corticobasal syndrome showing extensive Pittsburgh compound B uptake. J Neurol. 260 (8): 1982-91, 2013
・Satoh J, Tabunoki H, Ishida T, Saito Y, Arima K. Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains. Neuropathol Appl Neurobiol. 39 (7): 817-30, 2013
・Otsuki T, Honda R, Takahashi A, Kaido T, Kaneko Y, Nakai T, Saito Y, Itoh M, Nakagawa E, Sugai K, Sasaki M. Surgical management of cortical dysplasia in infancy and early childhood. Brain Dev. 35 (8): 802-9, 2013
・Kawana N, Yamamoto Y, Ishida T, Saito Y, Konno H, Arima K, Satoh J: Reactive astrocytes and perivascular macrophages express NLRP3 inflammasome in active demyelinating lesions of multiple sclerosis and necrotic lesions of neuromyelitis optica and cerebral infarction. Clinic Exp Neuroimmnol. 4: 296-304, 2013
・Funabe S, Takao M, Saito Y, Hatsuta H, Sugiyama M, Ito S, Kanemaru K, Sawabe M, Arai T, Mochizuki H, Hattori N, Murayama S. Neuropathologic analysis of Lewy-related α-synucleinopathy in olfactory mucosa. Neuropathology. 33(1): 47-58, 2013

《 2014 》
・Hasegawa M, Watanabe S, Kondo H, Akiyama H, Mann DM, Saito Y, Murayama S. 3R and 4R tau isoforms in paired helical filaments in Alzheimer's disease. Acta Neuropathol. 127 (2): 303-5, 2014
・Satoh J, Kino Y, Kawana N, Yamamoto Y, Ishida T, Saito Y, Arima K. TMEM106B expression is reduced in Alzheimer's disease brains. Alzheimers Res Ther, 6 (2): 17, doi: 10.1186/alzrt247. 2014
・Satoh J, Motohashi N, Kino Y, Ishida T, Yagishita S, Jinnai K, Arai N, Nakamagoe K, Tamaoka A, Saito Y, Arima K. LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains. Orphanet J Rare Dis. 9: 68, doi: 10.1186/1750-1172-9-68. 2014
・Satoh J, Kino Y, Yamamoto Y, Kawana N, Ishida T, Saito Y, Arima K. PLD3 is accumulated on neuritic plaques in Alzheimer's disease brains. Alzheimers Res Ther. 6 (9): 70, doi: 10.1186/s13195-014-0070-5. 2014
・Sakurai K, Tokumaru AM, Nakatsuka T, Murayama S, Hasebe S, Imabayashi E, Kanemaru K, Takao M, Hatsuta H, Ishii K, Saito Y, Shibamoto Y, Matsukawa N, Chikui E, Terada H. Imaging spectrum of sporadic cerebral amyloid angiopathy: multifaceted features of a single pathological condition. Insights Imaging. 5 (3): 375-85, 2014
・Miyashita A, Hatsuta H, Kikuchi M, Nakaya A, Saito Y, Tsukie T, Hara N, Ogishima S, Kitamura N, Akazawa K, Kakita A, Takahashi H, Murayama S, Ihara Y, Ikeuchi T, Kuwano R: Japanese Alzheimer's Disease Neuroimaging Initiative. Genes associated with the progression of neurofibrillary tangles in Alzheimer's disease. Transl Psychiatry. 4:e396, doi: 10.1038/tp.2014.35. 2014
・Kamiya K, Sato NU, Saito Y, Nakata Y, Ito K, Shigemoto Y, Ota M, Sasaki M, Ohtomo K. Accelerated myelination along fiber tracts in patients with hemimegalencephaly. J Neuroradiol. 41 (3): 202-10, 2014
・Miyashita A, Wen Y, Kitamura N, Matsubara E, Kawarabayashi T,Shoji M,Tomita N, Furukawa K, Arai H, Asada T, Harigaya Y,I keda M, Amari M, Hanyu H, Higuchi S, Nishizawa M, Suga M, Kawase Y, Akatsu H, Imagawa M, Hamaguchi T, Yamada M, Morihara T, Takeda M, Takao T, Nakata K, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Saito Y, Hatsuta H, Murayama S, Kakita A, Takahashi H, Yamaguchi H, Akazawa K, Kanazawa I, Ihara Y, Ikeuchi T, Kuwano R. Lack of genetic association between TREM2 and late-onset Alzheimer’s disease in a Japanese population. J Alzheimers Dis. 41 (4): 1031-8, 2014
・Matsumoto H, Sengoku R, Saito Y, Kakuta Y, Murayama S, Imafuku I. Sudden death in Parkinson's disease: a retrospective autopsy study. J Neurol Sci. 343 (1-2): 149-52, 2014
・Sukigara S, Dai H, Nabatame S, Otsuki T, Hanai S, Honda R, Saito T, Nakagawa E, Kaido T, Sato N, Kaneko Y, Takahashi A, Sugai K, Saito Y, Sasaki M, Goto Y, Koizumi S, Itoh M. Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy. J Neuropathol Exp Neurol. 73 (8): 798-806, 2014
・Ito S, Takao M, Hatsuta H, Kanemaru K, Arai T, Saito Y, Fukayama M, Murayama S. Alpha-synuclein immunohistochemistry of gastrointestinal and biliary surgical specimens for diagnosis of Lewy body disease. Int J Clin Exp Pathol, 7(4): 1714-23, 2014

《 2015 》
・Satoh J, Kino Y, Motohashi N, Ishida T, Yagishita S, Jinnai K, Arai N, Nakamagoe K, Tamaoka A, Saito Y, Arima K. Immunohistochemical characterization of CD33 expression on microglia in Nasu-Hakola disease brains. Neuropathology. 35 (6): 529-37, 2015
・Kitano S, Kino Y, Yamamoto Y, Takitani M, Miyoshi J, Ishida T, Saito Y, Arima K, Satoh J. Bioinformatics data mining approach suggests coexpression of AGTPBP1 with an ALS-linked gene C9orf72. J Cent Nerv Syst Dis. 7: 15-26, 2015
・Kimura Y, Sato N, Saito Y, Ito K, Kamiya K, Nakata Y, Watanabe M, Maikusa N, Matsuda H, Sugimoto H. Temporal lobe epilepsy with unilateral amygdala enlargement: morphometric MR analysis with clinical and pathological study. J Neuroimaging. 25 (2): 175-83, 2015
・Adachi Y, Sato N, Saito Y, Kimura Y, Nakata Y, Ito K, Kamiya K, Matsuda H, Tsukamoto T, Ogawa M. Usefulness of SWI for the detection of iron in the motor cortex in amyotrophic lateral sclerosis. J Neuroimaging. 25: 443-51, 2015
・Kuninaka N, Kawaguchi M, Ogawa M, Sato A, Arima K, Murayama S, Saito Y: Simplification of the modified Gallyas method. Neuropathology. 35: 10–5, 2015
・Shioya A, Saito Y, Arima K, Kakuta Y, Yuzuriha T, Tanaka N, Murayama S, Tamaoka A. Neurodegenerative changes in patients with clinical history of bipolar disorders. Neuropathology. 35 (3): 245-53, 2015
・Hatsuta H, Takao M, Ishii K, Ishiwata K, Saito Y, Kanemaru K, Arai T, Suhara T, Shimada H, Shinotoh H, Tamaoka A, Murayama S. Amyloid β accumulation assessed with ¹¹C-Pittsburgh compound B PET and postmortem neuropathology. Curr Alzheimer Res. 12 (3): 278-86, 2015
・Fukasawa T, Kubota T, Negoro T, Maruyama S, Honda R, Saito Y, Itoh M, Kakita A, Sugai K, Otsuki T, Kato M, Natsume J, Watanabe K. Two siblings with cortical dysplasia: clinico-electroencephalographic features. Pediatr Int. 57 (3): 472-5, 2015
・Uchino A, Takao M, Hatsuta H, Sumikura H, Nakano Y, Nogami A, Saito Y, Arai T, Nishiyama K, Murayama S. Incidence and extent of TDP-43 accumulation in aging human brain. Acta Neuropathol Commun. 3: 35, doi: 10.1186/s40478-015-0215-1. 2015
・Sumikura H, Takao M, Hatsuta H, Ito S, Nakano Y, Uchino A, Nogami A, Saito Y, Mochizuki H, Murayama S. Distribution of α-synuclein in the spinal cord and dorsal root ganglia in an autopsy cohort of elderly persons. Acta Neuropathol Commun. 3: 57, doi: 10.1186/s40478-015-0215-1. 2015
・Nogami A, Yamazaki M, Saito Y, Hatsuta H, Sakiyama S, Takao M, Kimura K, Murayama S. Early stage of progressive supranuclear palsy: neuropathological study of 324 consecutive autopsy cases. J Nippon Med Sch. 82 (6): 266-73, 2015
・Ishigami A, Masutomi H, Handa S, Nakamura M, Nakaya S, Uchida Y, Saito Y, Murayama S, Jang B, Jeon YC, Choi EK, Kim YS, Kasahara Y, Maruyama N, Toda T. Mass spectrometric identification of citrullination sites and immunohistochemical detection of citrullinated glial fibrillary acidic protein in Alzheimer's disease brains. J Neurosci Res. 93 (11): 1664-74, 2015

《 2016 》
・Satoh JI, Kino Y, Asahina N, Takitani M, Miyoshi J, Ishida T, Saito Y. TMEM119 marks a subset of microglia in the human brain. Neuropathology, 36 (1): 39-49, 2016
・Koichihara R, Saito T, Ishiyama A, Komaki H, Yuasa S, Saito Y, Nakagawa E, Sugai K, Shiihara T, Shioya A, Saito Y, Higuchi Y, Hashiguchi A, Takashima H, Sasaki M. A mild case of giant axonal neuropathy without central nervous system manifestation. Brain Dev. 38 (3): 350-3, 2016
・Saito Y, Shioya A, Sano T, Sumikura H,Murata M, Murayama S. Lewy body pathology involves the olfactory cells in Parkinson’s disease and related disorders. Mov Disord. 31 (1): 135-8, 2016
・Taniguchi-Watanabe S, Arai T, Kametani F, Nonaka T, Masuda-Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M, Akiyama H, Robinson A, Mann DM, Iwatsubo T, Hasegawa M. Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau. Acta Neuropathol. 131 (2): 267-80, 2016
・Sone D, Sato N, Yokoyama K, Sumida K, Kanai M, Imabayashi E, Saito Y, Matsuda H. Striatal glucose hypometabolism in preadolescent-onset dentatorubral-pallidoluysian atrophy. J Neurol Sci. 360: 121-4, 2016
・Kametani F, Obi T, Shishido T, Akatsu H, Murayama S, Saito Y, Yoshida M, Hasegawa M. Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains. Sci Rep. 6: 23281, doi: 10.1038/srep23281. 2016
・Satoh JI, Kino Y, Yanaizu M, Tosaki Y, Sakai K, Ishida T, Saito Y. Expression of gp91phox and p22phox, catalytic subunits of NADPH oxidase, on microglia in Nasu-Hakola disease brains. Intractable Rare Dis Res. 5(4): 275-9, 2016

《 2017 》
・Tomioka I, Ishibashi H, Minakawa EN, Motohashi HH, Takayama O, Saito Y, Popiel HA, Puentes S, Owari K, Nakatani T, Nogami N, Yamamoto K, Noguchi S, Yonekawa T, Tanaka Y, Fujita N, Suzuki H, Kikuchi H, Aizawa S, Nagano S, Yamada D, Nishino I, Ichinohe N, Wada K, Kohsaka S, Nagai Y, Seki K. Transgenic monkey model of the polyglutamine diseases recapitulating progressive neurological symptoms. eNeuro. 4 (2), doi: 10.1523/ENEURO.0250-16.2017. eCollection 2017
・Honma N, Saji S, Mikami T, Yoshimura N, Mori S, Saito Y, Murayama S, Harada N. Estrogen-related factors in the frontal lobe of Alzheimer's disease patients and importance of body mass index. Sci Rep. 7 (1): 726, doi: 10.1038/s41598-017-00815-3. 2017
・Morimoto S, Takao M, Hatsuta H, Nishina Y, Komiya T, Sengoku R, Nakano Y, Uchino A, Sumikura H, Saito Y, Kanemaru K, Murayama S. Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer's disease: an autopsy-confirmed study. PLoS One. 12 (2): e0171524, doi: 10.1371/journal.pone.0171524. eCollection 2017
・Hara N, Kikuchi M, Miyashita A, Hatsuta H, Saito Y, Kasuga K, Murayama S, Ikeuchi T, Kuwano R. Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer's disease. Acta Neuropathol Commun. 5 (1): 10, doi: 10.1186/s40478-017-0414-z, 2017
・Akasaka-Manya K, Kawamura M, Tsumoto H, Saito Y, Tachida Y, Kitazume S, Hatsuta H, Miura Y, Hisanaga SI, Murayama S, Hashimoto Y, Manya H, Endo T. Excess APP O-glycosylation by GalNAc-T6 decreases Aβ production. J Biochem. 161(1): 99-111, 2017
・Sugiyama A, Sato N, Kimura Y, Maekawa T, Enokizono M, Saito Y, Takahashi Y, Matsuda H, Kuwabara S. MR imaging features of cerebellum in adult-onset neuronal intranuclear inclusion disease: Eight cases. AJNR Am J Neuroradiol. 38 (11): 2100-4, 2017
・Araki W, Hattori K, Kanemaru K, Yokoi Y, Omachi Y, Takano H, Sakata M, Yoshida S, Tsukamoto T, Murata M, Saito Y, Kunugi H, Goto YI, Nagaoka U, Nagao M, Komori T, Arima K, Ishii K, Murayama S, Matsuda H, Tachimori H, Araki YM, Mizusawa H. Re-evaluation of soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for early diagnosis of dementia disorders. Biomark Res. 5: 28, doi: 10.1186/s40364-017-0108-5. eCollection 2017
・Satoh JI, Kino Y, Yanaizu M, Tosaki Y, Sakai K, Ishida T, Saito Y. Microglia express ABI3 in the brains of Alzheimer's disease and Nasu-Hakola disease. Intractable Rare Dis Res. 6 (4): 262-8, 2017
・Satoh JI, Kino Y, Yanaizu M, Tosaki Y, Sakai K, Ishida T, Saito Y. Expression of GPR17, a regulator of oligodendrocyte differentiation and maturation, in Nasu-Hakola disease brains. Intractable Rare Dis Res. 6 (1): 50-4, 2017

《 2018 》
・Satoh JI, Kino Y, Yanaizu M, Saito Y. Alzheimer's disease pathology in Nasu-Hakola disease brains. Intractable Rare Dis Res. 7(1): 32-6, 2018
・Kitamura Y, Komori T, Shibuya M, Ohara K, Saito Y, Hayashi S, Sasaki A, Nakagawa E, Tomio R, Kakita A, Nakatsukasa M, Yoshida K, Sasaki H. Comprehensive genetic characterization of rosette-forming glioneuronal tumors: independent component analysis by tissue microdissection. Brain Pathol. 28 (1): 87-93, 2018
・Sumitomo N Ishiyama A, Shibuya M, Nakagawa E, Kaneko Y, Takahashi A, Ohtsuki T, Kakita A, SaitoY, Sato N, Sugai K, Sasaki M. Intractable epilepsy due to a rosette-forming glioneuronal tumor with a dysembryoplastic neuroepithelial background. Neuropathology. 38 (3): 300-4, 2018
・Ishiyama A, Kimura Y, Saito Y, Miyamoto Y, Okada M, Sato N, Nishino I, Sasaki M. Transient swelling in the globus pallidus and substantia nigra in childhood suggests SENDA/BPAN. Neurology. 90 (21): 974-76, 2018